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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Intestinal endogenous metabolites affect neuroinflammation in 5×FAD mice by mediating “gut-brain” axis and the intervention with Chinese Medicine

Fig. 6

Alterations of gut-derived metabolites in feces of 5×FAD mice with age. (A) gut-derived metabolites of feces changed in a senescence dependent manner. (B) Correlation analysis between gut-derived metabolites and SCFAs. n = 6–9. Difference was analyzed by Two-tested Student’s t test and donated as follows: *p < 0.05, **p < 0.01, ***p < 0.001. 5-OH indoleacetic acid: 5 HIAA; 5-hydroxytryptophan: 5 HT; Acetic acid: AA; Alanine: Ala; Arginine: Arg; Aspartic acid: Asp; Butyric acid: BA; Citrulline: Cit; Choline: Cho; Glutamic acid: Glu; Glutamine: Gln; Histidine: His; Hexanoic acid: HA; Iso-valeric acid: IVA; Iso-butyric acid: IBA; Lysine: Lys; Leucine: Leu; L-Cysteine: L-Cys; Methionine: Met; Propionic acid: PA; Phenylalanine: PHE; Proline: Pro; Serine: Ser; Taurine: Tau; Tryptophan: Trp; Tyrosine: Tyr; Valeric acid: VA

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Alzheimer's Research & Therapy

ISSN: 1758-9193