Fig. 4

Association between seven psychosocial patterns and dementia of any type, by APOE ε4 genotype, polygenic risk score, and family history of dementia. HRs and 95% CIs were derived from Cox regression models, adjusted for gender, ethnicity, smoking, alcohol drinking, hours of sleep, physical activities, body mass index, Charlson comorbidity index, history of hypertension and hyperlipidemia, grip strength, and hearing loss state. Abbreviations: HR, hazard ratio; CI, confidence interval; PRS, polygenic risk score