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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Sex-specific risk factors and clinical dementia outcomes for white matter hyperintensities in a large South Korean cohort

Fig. 1

Older females appear to have an accelerated increase in cerebrovascular burden as they age and are more susceptible to the cerebrovascular consequences of diabetes. A.) Females are observed to have a higher increase in WMHV as they age compared to males. B.) Diabetic females were associated with larger WMHV compared to non-diabetic females. There were no differences observed for males. For visualization purposes, WMHV is plotted versus age and grouped by sex and type 2 diabetes status. C.) Higher HbA1c levels were associated with larger WMHV for females but not males, but the interaction effect for HbA1c*sex did not survive multiple comparisons. WMHV = white matter hyperintensity volume

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