Table 2 Baseline demographics of healthy volunteers in the phase 1 study
AL002 | Total AL002 (n = 53) | Pooled Placebo (n = 11) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
0.003-0.2 mg/kg (n = 3) | 0.6 mg/kg (n = 6) | 2 mg/kg (n = 6) | 6 mg/kg (n = 6) | 15 mg/kg (n = 6) | 30 mg/kg (n = 6) | 45 mg/kg (n = 6) | 60 mg/kg (n = 14) | |||
Age, years Mean (SD) Min, max | 41.7 (16.86) 30, 61 | 26.0 (3.69) 21, 31 | 31.2 (13.38) 23, 58 | 31.8 (11.91) 23, 53 | 32.7 (3.78) 28, 38 | 32.7 (16.11) 22, 65 | 32.3 (14.25) 21, 60 | 32.7 (10.55) 20, 51 | 32.1 (11.35) 20, 65 | 39.7 (15.86) 22, 65 |
Sex, n (%) Female Male | 0 3 (100) | 4 (66.7) 2 (33.3) | 2 (33.3) 4 (66.7) | 2 (33.3) 4 (66.7) | 4 (66.7) 2 (33.3) | 5 (83.3) 1 (16.7) | 4 (66.7) 2 (33.3) | 10 (71.4) 4 (28.6) | 31 (58.5) 22 (41.5) | 8 (72.7) 3 (27.3) |
Race, n (%) White Asian Black/African American Other | 3 (100.0) 0 0 0 | 4 (66.7) 2 (33.3) 0 0 | 4 (66.7) 1 (16.7) 0 1 (16.7) | 4 (66.7) 0 0 2 (33.3) | 4 (66.7) 1 (16.7) 0 1 (16.7) | 5 (83.3) 0 0 1 (16.7) | 3 (50.0) 2 (33.3) 0 1 (16.7) | 10 (71.4) 0 3 (21.4) 1 (7.1) | 37 (69.8) 6 (11.3) 3 (5.7) 7 (13.2) | 11 (100.0) 0 0 0 |
Hispanic/Latino ethnicity, n (%) | 1 (33.3) | 0 | 0 | 2 (33.3) | 1 (16.7) | 1 (16.7) | 1 (16.7) | 2 (14.3) | 8 (15.1) | 2 (18.2) |
Screening BMI, kg/m2, mean (SD) | 24.90 (1.212) | 23.53 (1.834) | 24.88 (3.142) | 24.32 (3.159) | 24.47 (1.245) | 23.97 (1.266) | 28.00 (5.829) | 25.41 (4.359) | 25.01 (3.486) | 24.45 (3.839) |