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Table 1 Demographic characteristics of unrelated ADNI participants with European ancestry

From: Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites

Cohorts

ADNI-1

ADNI-GO

ADNI-2

Total, No.

585

109

661

Age, mean (SD), y

74.8 (6.8)

71.5 (7.6)

72.4 (7.1)

Female, No. (%)

233 (39.8%)

47 (43.1%)

307 (46.4%)

Baseline Diagnosis, No. (%)

   

 CN

161 (27.5%)

-

238 (36.0%)

 MCI

301 (51.5%)

109 (100%)

300 (45.4%)

 AD

123 (21.0%)

-

123 (18.6%)

Progression from CN to MCI, No. (%)

   

 Yes

38 (26.2%)

-

25 (11.7%)

 No

107 (73.8%)

-

189 (88.3%)

Progression from MCI to AD, No. (%)

   

 Yes

155 (57.2%)

12 (14.6%)

77 (30.8%)

 No

116 (42.8%)

70 (85.4%)

173 (69.2%)

  1. SD Standard deviation, CN Cognitively normal, MCI Mild cognitive impairment, AD Alzheimer’s Disease, ADNI the Alzheimer’s Disease Neuroimaging Initiative