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Table 2 Estimation of causal effect of blood mtDNA-CN on AD using two-sample mendelian randomization methods

From: Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites

Method

OR

95% CI

P-value

Robust adjusted profile score

0.677

0.498–0.920

0.013

MR Egger

0.478

0.246–0.928

0.041

Weighted median

0.746

0.494–1.125

0.162

Inverse variance weighted

0.700

0.495–0.991

0.044

  1. SE Standard error, 95% CI 95% confidence interval
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Alzheimer's Research & Therapy

ISSN: 1758-9193