Table 3 Diagnosis utility of combination of Neucop-Q on account of amyloid or tau PET positivity
All participants | Participants without Amyloid PET + | |||||||
|---|---|---|---|---|---|---|---|---|
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cimp/Pimp/Nimp | 6 | 11 | 0.353 | PPV | Cimp/Pimp/Nimp | 5 | 5 | 0.500 |
other | 43 | 95 | 0.688 | NPV | other | 44 | 43 | 0.494 |
0.122 | 0.896 | 0.102 | 0.896 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cnor/Pimp/Nimp | 2 | 3 | 0.400 | PPV | Cnor/Pimp/Nimp | 2 | 1 | 0.667 |
other | 47 | 103 | 0.687 | NPV | other | 47 | 47 | 0.500 |
0.041 | 0.972 | 0.041 | 0.979 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cimp/Pnor/Nimp | 15 | 3 | 0.833 | PPV | Cimp/Pnor/Nimp | 1 | 2 | 0.333 |
other | 34 | 103 | 0.752 | NPV | other | 48 | 46 | 0.489 |
0.306 | 0.972 | 0.020 | 0.958 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cimp/Pimp/Nnor | 2 | 5 | 0.286 | PPV | Cimp/Pimp/Nnor | 4 | 1 | 0.800 |
other | 47 | 101 | 0.682 | NPV | other | 45 | 47 | 0.511 |
0.041 | 0.953 | 0.082 | 0.979 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cnor/Pnor/Nimp | 5 | 8 | 0.385 | PPV | Cnor/Pnor/Nimp | 5 | 2 | 0.714 |
other | 44 | 98 | 0.690 | NPV | other | 44 | 46 | 0.511 |
0.102 | 0.925 | 0.102 | 0.958 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cnor/Pimp/Nnor | 0 | 3 | 0.000 | PPV | Cnor/Pimp/Nnor | 3 | 0 | ∞ |
other | 49 | 103 | 0.678 | NPV | other | 46 | 48 | 0.511 |
0.000 | 0.972 | 0.061 | ∞ | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cimp/Pnor/Nnor | 10 | 27 | 0.270 | PPV | Cimp/Pnor/Nnor | 10 | 12 | 0.455 |
other | 39 | 79 | 0.669 | NPV | other | 39 | 36 | 0.480 |
0.204 | 0.745 | 0.204 | 0.750 | |||||
sens. | spec. | sens. | spec. | |||||
AD or AD-MCI | non-AD Tau PET | |||||||
(+) | (-) | (+) | (-) | |||||
Cnor/Pnor/Nnor | 9 | 46 | 0.164 | PPV | Cnor/Pnor/Nnor | 19 | 25 | 0.432 |
other | 40 | 60 | 0.600 | NPV | other | 30 | 23 | 0.434 |
0.184 | 0.566 | 0.388 | 0.479 | |||||
sens. | spec. | sens. | spec. | |||||