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Table 1 Participant characteristics

From: Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer’s disease

Participant characteristics

All

Females

Males

p value

Effect size

N

660

408

252

Age (y)

52.0 (9.0)

52.0 (8.0)

53.0 (10.0)

0.03

0.08

Race (% Caucasian)

95.9%

95.8%

96.0%

0.99

< 0.001

BMI

27.0 (6.5)

(n = 659)

26.3 (7.2)

(n = 407)

27.8 (4.7) (n = 252)

< 0.001

0.15

Hypertension (%)

17.1%

11.3%

26.6%

< 0.001

0.19

Hyperlipidemia (%)

23.4% (n = 644)

21.3%

(n = 395)

26.9% (n = 249)

0.12

0.06

Poor sleep (%)

51.8%

(n = 657)

52.6%

(n = 407)

50.4%

(n = 250)

0.64

0.02

Current smoker (%)

5.8% (n = 657)

4.7%

(n = 405)

7.5%

(n = 252)

0.18

0.05

High alcohol intake (%)

17.4% (n = 655)

12.1%

(n = 405)

26.0% (n = 250)

< 0.001

0.17

APOE4 (% Carriers)

38.2%

38.0%

38.5%

0.96

0.002

Years of education

17.0 (5.0)

17.0 (5.0)

17.0 (3.0)

0.18

0.05

Stimulating activities

18.0 (5.0)

18.0 (5.0)

18.0 (4.0)

0.19

0.05

Occupational attainment

13.8 (6.3)

12.6 (7.1)

15.0 (6.3)

< 0.001

0.21

Episodic and relational memory

0.001 (1.0)

0.17 (1.0)

-0.28 (1.0)

< 0.001

0.47

Multisensory processing

-4e-5 (1.0)

0.01 (1.0)

-0.02 (1.1)

0.70

0.03

Short-term memory binding

0.12 (1.1)

0.09 (1.1)

0.15 (1.0)

0.39

0.03

  1. Note: median (interquartile range, IQR) was reported for non-normal distributed continuous variables. Mean (SD) was reported for normal distributed continuous variables. Effect size was determined using r for Mann-Whitney U test, Cohen’s d for independent samples t-test and φ for the Chi-Square test. Abbreviations: BMI, body mass index; APOE4, Apolipoprotein E4 genotype