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Table 3 Regression coefficients for models including 2-way or 3-way interactions of IVs on episodic and relational memory

From: Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer’s disease

Model A: 2-way interaction

Model summary

R2

F

p value

0.14

17.76

< 0.001

DV

IV

β (SE)

95% CI

p value

Episodic and relational memory

Occupational attainment

-0.08 (0.06)

[-0.20, 0.05]

0.23

Sex

0.40 (0.08)

[0.25, 0.55]

< 0.001

Years of education

0.05 (0.01)

[0.03, 0.07]

< 0.001

Stimulating activities

0.05 (0.01)

[0.03, 0.07]

< 0.001

Age

-0.02 (0.01)

[-0.03, -0.004]

0.01

Sex*Occupational attainment

0.14 (0.08)

[-0.007, 0.29]

0.06

Model B: 3-way interaction

Model summary

R2

F

p value

0.15

11.75

< 0.001

DV

IV

β (SE)

95% CI

value

Episodic and relational memory

APOE4

0.03 (0.12)

[-0.22, 0.27]

0.83

Sex

0.31 (0.10)

[0.12, 0.51]

0.001

Occupational attainment

-0.01 (0.08)

[-0.17, 0.14]

0.87

APOE4*Sex

0.22 (0.16)

[-0.08, 0.53]

0.16

APOE4*Occupational attainment

-0.19 (0.12)

[-0.43, 0.06]

0.13

Sex*Occupational attainment

0.03 (0.09)

[-0.16, 0.21]

0.78

APOE4*Sex*Occupational attainment

0.33 (0.16)

[0.02, 0.64]

0.037

Years of education

0.05 (0.01)

[0.02, 0.07]

< 0.001

Stimulating activities

0.05 (0.01)

[0.03, 0.07]

< 0.001

Age

-0.02 (0.01)

[-0.03, -0.002]

0.03

  1. Note: Unstandardized coefficients β and standard error (SE) were reported. DV, dependent variable; IV, independent variable; CI, confidence intervals