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Table 3 Methods and scales to assess secondary outcomes

From: A digitally supported multimodal lifestyle program to promote brain health among older adults (the LETHE randomized controlled feasibility trial): study design, progress, and first results

• Lifestyle/adherence to healthy lifestyle: Composite score developed in FINGER, based on self-reported data on exercise, diet, vascular factors, and cognitive/social activity (Barbera et al., Alzheimer’s & Dementia, 2021. doi:https://doiorg.publicaciones.saludcastillayleon.es/10.1002/alz.053388)

• Stress-related symptoms: Perceived Stress Scale-14 (Cohen et al., Journal of Health and Social Behavior, 1983. doi:https://doiorg.publicaciones.saludcastillayleon.es/10.1002/alz.05338810.2307/2136404)

• Sleep problems: Insomnia Severity Index (Morin, Insomnia: Psychological assessment and management, 1993)

• Health-related quality of life: RAND-36 scale (Hays et al., Health Econ, 1993. doi:https://doiorg.publicaciones.saludcastillayleon.es/10.1002/hec.4730020305)

• Health literacy: 16-item European Health Literacy Survey Questionnaire (Sørensen et al., Eur J Public Health, 2015. doi: https://doiorg.publicaciones.saludcastillayleon.es/10.1093/eurpub/ckv043)

• Cognitive performance: Composite z-score of the following 14 NTB tests: WMS-III, WMS-R, WMS-IV Logical Memory, immediate; Logical Memory, delayed; WMS-R Visual Paired Associates, immediate; Visual Paired Associates, delayed; Digit Span; RAVLT learning; RAVLT delayed recall; CERAD category fluency; Category fluency fruits and vegetables; TMT A; TMT B (shifting score B–A); Shortened 40-stimulus Stroop Test condition 2; Stroop test condition 3 (interference score 3–2); WAIS-IV Digit Symbol Substitution Test

  1. Abbreviations: CERAD Consortium to Establish a Registry for Alzheimer's Disease, FINGER Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability, NTB Neuropsychological Test Battery, RAVLT Rey Auditory Verbal Learning Test, TMT Trail Making Test, WAIS Wechsler Adult Intelligence Scale, WMS Wechsler Memory Scale
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Alzheimer's Research & Therapy

ISSN: 1758-9193