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Table 4 Partial correlation of CT measured with MMSE scores

From: Changes in choroidal thickness quantified by Optical Coherence Tomography across cognitive impairment: data from the NORFACE cohort

Diagnostic groups

Variable

R

Significance

Whole sample (n = 1280)

Center

0.04

0.184

In Temporal

0.03

0.310

In Superior

0.03

0.375

In Nasal

0.03

0.318

In Inferior

0.03

0.254

Out Temporal

0.03

0.299

Out Superior

0.03

0.277

Out Nasal

0.03

0.294

Out Inferior

0.03

0.315

Average thickness

-0.04

0.209

Subfoveal choroidal thickness

-0.02

0.575

Total volume

-0.03

0.339

CU (n = 301)

Center

0.02

0.764

In Temporal

0.02

0.699

In Superior

0.02

0.741

In Nasal

0.03

0.665

In Inferior

0.01

0.806

Out Temporal

0.02

0.712

Out Superior

0.02

0.714

Out Nasal

0.02

0.743

Out Inferior

0.02

0.712

Average thickness

-0.01

0.928

Subfoveal choroidal thickness

-0.01

0.918

Total volume

-0.03

0.584

MCI-AD (n = 196)

Center

-0.07

0.365

In Temporal

0.01

0.978

In Superior

0.01

0.889

In Nasal

-0.01

0.947

In Inferior

0.04

0.624

Out Temporal

0.01

0.988

Out Superior

0.01

1.000

Out Nasal

0.01

0.972

Out Inferior

-0.01

0.971

Average thickness

0.12

0.126

Subfoveal choroidal thickness

0.10

0.208

Total volume

-0.04

0.625

MCI-Va (n = 112)

Center

-0.02

0.846

In Temporal

-0.02

0.886

In Superior

-0.01

0.982

In Nasal

-0.02

0.856

In Inferior

-0.02

0.863

Out Temporal

-0.02

0.849

Out Superior

-0.02

0.868

Out Nasal

-0.02

0.874

Out Inferior

-0.02

0.859

Average thickness

0.17

0.105

Subfoveal choroidal thickness

0.01

0.921

Total volume

-0.02

0.830

ADD (n = 578)

Center

0.03

0.531

In Temporal

0.03

0.496

In Superior

0.02

0.646

In Nasal

0.02

0.570

In Inferior

0.01

0.778

Out Temporal

0.02

0.646

Out Superior

0.02

0.638

Out Nasal

0.02

0.623

Out Inferior

0.02

0.610

Average thickness

-0.08

0.077

Subfoveal choroidal thickness

-0.01

0.863

Total volume

-0.02

0.692

VaD (n = 93)

Center

0.04

0.768

In Temporal

0.01

0.921

In Superior

-0.01

0.960

In Nasal

0.01

0.929

In Inferior

0.01

0.999

Out Temporal

0.01

0.945

Out Superior

0.01

0.906

Out Nasal

0.01

0.931

Out Inferior

0.01

0.929

Average thickness

-0.01

0.948

Subfoveal choroidal thickness

-0.03

0.809

Total volume

-0.01

0.949

  1. The model included the following adjusting factors: age, sex, years of education, hypertension, diabetes mellitus, heart disease, COPD, stroke, smoking and image quality. Significance was set up at p < 0.05
  2. Abbreviations: ADD Alzheimer ́s disease dementia, CT Choroidal thickness, CU Cognitively unimpaired, CV Cerebrovascular, MCI-AD Mild cognitive impairment due to Alzheimer ́s disease, MCI-Va Mild cognitive impairment due to CV pathology, OCT Optical coherence tomography, VaD Vascular dementia
  3. Regions in the ETDRS grid are divided into "Inner" and "Outer" zones, with "Inner" representing CT measurements within a 3 mm radius and "Outer" representing CT measurements within a 6 mm radius, corresponding to specific areas used for CT measurements in the study. The abbreviations used in the table are as follows: In Temporal = Inner Temporal, In Superior = Inner Superior, In Nasal = Inner Nasal, In Inferior = Inner Inferior. Similarly, Out Temporal = Outer Temporal, Out Superior = Outer Superior, Out Nasal = Outer Nasal, and Out Inferior = Outer Inferior