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Fig. 10 | Alzheimer's Research & Therapy

Fig. 10

From: Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches

Fig. 10

DSS improved mitochondrial function and relieved oxidative stress in APP/PS1 mice. (A) MMP measurement. (B,C) ATP and NADH content (n = 6). (D-G) Mitochondrial respiratory chain I-IV content. (H-J) The relative content of ROS, total SOD, and MDA. Data are presented as mean ± SEM, n = 6−9 mice per group. ##p < 0.01 vs. the control group. *p < 0.05, **p < 0.01 vs. the model group, ns, no significant difference. Con, control group; Mod, model group; LiC, inhibitor group; Don, positive control group; DH, high dose of DSS group; DM, medium dose of DSS group; DL, low dose of DSS group. One-way ANOVA, followed by LSD method multiple comparisons test (A, B, C, D, E, F, H, and I) or Tamhane’s T2 method test (G, J)

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Alzheimer's Research & Therapy

ISSN: 1758-9193