Skip to main content
Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches

Fig. 4

Drug-target network analysis and screening process of core ingredients in DSS. (A) This network comprises 6,514 DTIs, which interacts with 1,118 ingredients and 218 AD genes. The labels of the top 10 ingredients and AD genes with degrees ≥ 30 are shown. The font size of the labels and the size of the nodes are proportional to the degree. (B) Sankey diagram showing the screening process of the core ingredients in DSS. HIA, human intestinal absorption; BBB, blood-brain barrier; PPB, plasma protein binding. Herbal ingredients are classified according to the chemical taxonomy provided by ClassyFire [37]

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193