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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches

Fig. 7

Serum metabolic profile of APP/PS1 mice after DSS treatment (n = 6). (A) PCA and (B) OPLS-DA score plots between the control and model groups. (C) PCA and (D) OPLS-DA score plots between the model and high dose of DSS (DH) treatment group. (E) Heatmap of the 47 differential metabolites for three groups. (F) Schematic diagram of some detected metabolites associated with EM. (G,H) Volcano plot of differential metabolites of the control vs. model groups and the model vs. DH groups. (I) Change in the relative peak area of the metabolites. Data are expressed as mean ± SEM. n = 6 mice per group. #p < 0.05 vs. the control group. *p < 0.05 vs. the model group. **p < 0.01 vs. the model group

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Alzheimer's Research & Therapy

ISSN: 1758-9193