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Fig. 9 | Alzheimer's Research & Therapy

Fig. 9

From: Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches

Fig. 9

DSS promoted brain glucose uptake in APP/PS1 mice. (A-C) qPCR analysis showing the GLUT1, GLUT4, and BDNF levels in the cortex. (D-G) Protein expression levels of GLUT1, GLUT4, and BDNF in the cortex and hippocampus by western blot analysis. Data are shown as mean ± SEM, n = 3 mice per group. #p < 0.05, ##p < 0.01 vs. the control group. *p < 0.05, **p < 0.01 vs. the model group, ns, no significant difference. Con, control group; Mod, model group; LiC, inhibitor group; Don, positive control group; DH, high dose of DSS group; DM, medium dose of DSS group; DL, low dose of DSS group. One-way ANOVA, followed by LSD method multiple comparisons tests (A, B, C, E, and G)

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Alzheimer's Research & Therapy

ISSN: 1758-9193