Fig. 4

Forest plot summarizing the effect of AADvac1 on outcomes in plasma p-tau217 ‘positive’ participants. A mixed model for repeated measures (MMRM) analysis was performed for changes in cognitive, volumetric and plasma biomarker outcomes at 104 weeks. Percent differences between the AADvac1 and placebo groups were plotted along with 95% CIs (error bars). Ctx, cortex