Fig. 1

Panel (A) compares results of the causal effect of CETP inhibition on AD risk when using four different GWAS for AD. Panel (B) compares results of the causal effect of CETP inhibition on AD risk when scaling effects to CETP concentrations, increasing HDL cholesterol, and decreasing LDL cholesterol and triglycerides (TG), using the largest AD GWAS as the outcome (Bellenguez et al., 2022)