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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer’s disease and behavioral-variant frontotemporal dementia

Fig. 3

Comparison of the area under the curve (AUC) values of blood-based assays and biomarkers across three pairwise group comparisons: (A) Alzheimer’s disease (AD) vs. non-neurodegenerative controls (NNC), (B) behavioral variant frontotemporal dementia (bvFTD) vs. NNC, and (C) AD vs. bvFTD. The AUC for each biomarker was calculated from ROC analyses. Pairwise AUC comparisons were performed using the DeLong test. Each panel presents a heatmap showing AUC differences between biomarkers, with the point size reflecting the AUC value of the biomarker on the y-axis. The color intensity represents the absolute AUC difference between the biomarker on the y-axis and the corresponding biomarker on the x-axis. Statistically significant differences are labeled with significance levels: ***, **, and *, corresponding to p-values of ≤ 0.001, ≤ 0.01, and ≤ 0.05, respectively. Biomarkers are arranged by AUC from highest to lowest on the y-axis

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Alzheimer's Research & Therapy

ISSN: 1758-9193