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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer’s disease and behavioral-variant frontotemporal dementia

Fig. 4

Receiver operating characteristic (ROC) curves illustrating the diagnostic performance of two-biomarker combinations in distinguishing Alzheimer’s disease (AD) from behavioral variant frontotemporal dementia (bvFTD). AUC values were derived from logistic regression models for all possible two-biomarker combinations, including all assays and biomarkers in present study. The top five combinations, ranked by AUC, are presented. The analysis contrasts models with (A) and without (B) the inclusion of pTau-181. It should be noted that none of the biomarker combinations were significantly better than their individual counterparts, according to DeLong’s test

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Alzheimer's Research & Therapy

ISSN: 1758-9193