Table 1 Characteristics of 116 samples defined as P-MCI, S-MCI or AD
From: Transcriptomic predictors of rapid progression from mild cognitive impairment to Alzheimer's disease
ANCOVA | Post-hoc comparison | ||||||
|---|---|---|---|---|---|---|---|
Characteristic | S-MCI | P-MCI | AD | p value | P-MCI vs. S-MCI | AD vs. P-MCI | AD vs. S-MCI |
Sample (n) | 39 | 28 | 49 | - | |||
Age (years) | 69.6 ± 6.0 | 75.8 ± 8.0 | 75.8 ± 7.4 | * | ** | ns | *** |
Female (%) | 35.9 | 50.0 | 40.8 | - | ns | ns | ns |
Education (years) | 13.0 ± 3.8 | 11.8 ± 5.3 | 11.6 ± 4.2 | ns | - | - | - |
MMSE score | 27.7 ± 1.9 | 24.7 ± 1.6 | 21.5 ± 4.3 | *** | *** | *** | *** |
WMS-III Logical Memory Story A | 6.7 ± 4.0 | 1.4 ± 2.2 | 0.9 ± 1.6 | *** | *** | ns | *** |
CVVLT recall | 6.5 ± 1.9 | 1.9 ± 2.2 | 1.1 ± 1.6 | *** | *** | ns | *** |
TMT B time (sec) | 55.4 ± 32.6 | 73.6 ± 36.8 | 98.2 ± 29.7 | *** | ns | * | *** |
TMT B lines | 13.4 ± 2.1 | 11.8 ± 3.5 | 10.0 ± 4.6 | * | ns | ns | * |
TY-CFT copy | 31.0 ± 3.8 | 30.6 ± 4.8 | 29.6 ± 6.6 | ns | - | - | - |
TY-CFT recall | 16.9 ± 6.9 | 5.3 ± 4.0 | 4.0 ± 4.7 | *** | *** | ns | *** |
BNT (30 items) | 27.9 ± 2.0 | 26.6 ± 2.5 | 22.8 ± 4.9 | *** | ns | *** | *** |
VF-animal | 15.8 ± 3.9 | 12.9 ± 4.3 | 10.8 ± 5.5 | *** | * | ns | *** |
APOE ε4 carrier (%) | 28.2 | 50.0 | 46.9 | - | ns | ns | ns |