Table 1 Patient’s characteristics at baseline by sex
Male | Female | p-value† | |
|---|---|---|---|
n = 1,735 | n = 4,373 | ||
Age | |||
<60 yrs | 38 (2.2%) | 59 (1.3%) | < 0.01 |
60–69 yrs | 114 (6.6%) | 219 (5.0%) | |
70–79 yrs | 495 (28.5%) | 1,209 (27.6%) | |
80–84 yrs | 566 (32.6%) | 1,351 (30.9%) | |
85 + yrs | 522 (30.1%) | 1,535 (35.1%) | |
mean (SD) | 80.2 (7.7) | 81.2 (7.2) | < 0.01 |
CDR | |||
CDR 1 | 1,175 (67.7%) | 2,641 (60.4%) | 0.01 |
CDR 2 | 491 (28.3%) | 1,520 (34.8%) | |
CDR 3 | 69 (4.0%) | 212 (4.8%) | |
MMSE | |||
MMSE > = 24 | 417 (24.0%) | 632 (14.5%) | < 0.01 |
MMSE 19–23 | 708 (40.8%) | 1,677 (38.3%) | |
MMSE 10–18 | 507 (29.2%) | 1,779 (40.7%) | |
MMSE < 10 | 87 (5.0%) | 247 (5.6%) | |
Missing | 16 (0.9%) | 38 (0.9%) | |
mean (SD) | 19.7 (5.2) | 18.4 (5.0) | < 0.01 |
Education | |||
No formal education | 191 (11.0%) | 1,017 (23.3%) | < 0.01 |
Primary School | 982 (56.6%) | 2,751 (62.9%) | |
Secondary School | 278 (16.0%) | 295 (6.7%) | |
University | 223 (12.9%) | 187 (4.3%) | |
Unknown | 61 (3.5%) | 123 (2.8%) | |
Marital status | |||
Married/Partnered | 1,328 (76.5%) | 1,628 (37.2%) | < 0.01 |
Widowed | 249 (14.4%) | 2,249 (51.4%) | |
Divorced/Separate | 43 (2.5%) | 123 (2.8%) | |
Single | 59 (3.4%) | 256 (5.9%) | |
Unknown | 56 (3.2%) | 117 (2.7%) | |
Cohabitation status | |||
Lives alone | 195 (11.2%) | 1,217 (27.8%) | 0.87 |
Lives with spouse/partner | 1,160 (66.9%) | 1,389 (31.8%) | |
Lives with someone (other) | 110 (6.3%) | 839 (19.2%) | |
Domestic group | 146 (8.4%) | 495 (11.3%) | |
Nursing home | 45 (2.6%) | 176 (4.0%) | |
Unknown | 79 (4.6%) | 257 (5.9%) | |
Caregiver | |||
None | 657 (37.9%) | 1,596 (36.5%) | < 0.01 |
Spouse/Partner | 553 (31.9%) | 482 (11.0%) | |
Son/Daughter | 90 (5.2%) | 536 (12.3%) | |
Professional | 126 (7.3%) | 504 (11.5%) | |
Residential Caregiver | 41 (2.4%) | 158 (3.6%) | |
Other | 268 (15.4%) | 1,097 (25.1%) | |
Comorbidity | |||
Depression | 234 (14.5%) | 1,434 (34.6%) | < 0.01 |
Epilepsy | 22 (1.3%) | 49 (1.2%) | 0.57 |
Pshycosis | 15 (0.9%) | 82 (2.0%) | 0.38 |
Copd | 272 (16.2%) | 433 (10.2%) | < 0.01 |
Arthrosis | 591 (35.1%) | 2,669 (62.8%) | < 0.01 |
Alcohol Abuse | 292 (17.5%) | 185 (4.4%) | < 0.01 |
Traumatic Brain Injury | 42 (2.6%) | 85 (2.0%) | 0.05 |
Thyroid Disease | 72 (4.3%) | 568 (13.5%) | < 0.01 |
CeVD | 202 (12.0%) | 364 (8.6%) | < 0.01 |
Heart Disease | 651 (38.8%) | 1,143 (27.0%) | < 0.01 |
Hyperlipaemia | 730 (43.2%) | 1,970 (46.2%) | 0.67 |
Diabetes Mellitus | 451 (26.7%) | 842 (19.7%) | < 0.01 |
Hypertension | 1,052 (62.0%) | 2,798 (65.4%) | 0.02 |
Kidney Disease | 210 (12.6%) | 415 (9.8%) | < 0.01 |
Peptic Ulcer | 317 (19.2%) | 729 (17.3%) | < 0.01 |
Smoking | 179 (10.6%) | 102 (2.4%) | < 0.01 |
Family History | |||
Dementia | 728 (42.8%) | 1,755 (40.9%) | 0.15 |
Huntington disease | 9 (0.6%) | 17 (0.4%) | 0.56 |
Parkinson disease | 61 (3.6%) | 130 (3.1%) | 0.52 |
Psychiatric disease | 87 (5.1%) | 296 (6.9%) | 0.4 |
Down syndrome | 11 (0.6%) | 25 (0.6%) | 0.38 |