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Table 2 Frequency of neuropsychiatric symptoms at baseline by sex

From: Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit

 

Male

Female

p-value†

N = 1,648

N = 4,134

Symptom

   

 Apathy/Indifference

1,162 (70.5%)

2,764 (66.9%)

< 0.01

 Hallucinations

100 (6.1%)

453 (11.0%)

< 0.01

 Anxiety

759 (46.1%)

2,441 (59.0%)

< 0.01

 Agitation/Aggression

249 (15.1%)

555 (13.4%)

< 0.01

 Aberrant Motor Behaviour

77 (4.7%)

236 (5.7%)

0.10

 Delusions

292 (17.7%)

1,125 (27.2%)

< 0.01

 Depression/Dysphoria

762 (46.2%)

2,530 (61.2%)

< 0.01

 Disinhibition

155 (9.4%)

269 (6.5%)

< 0.01

 Elation/Euphoria

27 (1.6%)

48 (1.2%)

0.36

 Appetite And Eating Disorders

200 (12.1%)

833 (20.1%)

< 0.01

 Irritability/Lability

1,000 (60.7%)

2,298 (55.6%)

< 0.01

 Sleep And Night-Time Behaviour

494 (30.0%)

1,361 (32.9%)

0.01

Mean number of NPS (SD)

3.20 (1.78)

3.61 (1.90)

0.09

  1. Abbreviations: NPS = neuropsychological symptoms; SD = standard deviation
  2. †Estimates adjusted for age at baseline, education, marital status, cohabitation status, type of caregiver, arthrosis, and depression using logistic regression models