Table 7 Time to any CDR increase during follow-up
Covariate | N | PY | failures | IR x 100 | HR (95%CI) * | P>|z| |
|---|---|---|---|---|---|---|
Sex | ||||||
Male | 1322 | 2799 | 971 | 34.7 | 1 | (ref) |
Female | 3379 | 7510 | 2535 | 33.8 | 0.96 (0.89–1.04) | 0.34 |
Age at baseline | ||||||
<60 | 66 | 139 | 57 | 41.0 | 1 | (ref) |
60–69 | 257 | 595 | 206 | 34.6 | 0.69 (0.52–0.93) | 0.02 |
70–79 | 1409 | 3357 | 1072 | 31.9 | 0.64 (0.49–0.84) | < 0.01 |
80–84 | 1512 | 3326 | 1133 | 34.1 | 0.69 (0.53–0.91) | 0.01 |
85+ | 1457 | 2892 | 1038 | 35.9 | 0.81 (0.62–1.07) | 0.14 |
CDR at baseline | ||||||
CDR 1 | 3225 | 6615 | 2726 | 41.2 | 1 | (ref) |
CDR 2 | 1476 | 3694 | 780 | 21.1 | 0.41 (0.38–0.45) | < 0.01 |
Education | ||||||
No formal education | 935 | 2099 | 676 | 32.2 | 1 | (ref) |
Primary School | 2923 | 6447 | 2187 | 33.9 | 0.93 (0.85–1.02) | 0.1 |
Secondary School | 453 | 946 | 340 | 35.9 | 0.91 (0.79–1.04) | 0.15 |
University | 314 | 653 | 248 | 38.0 | 0.92 (0.79–1.07) | 0.29 |
Unknown | 76 | 163 | 55 | 33.7 | 0.97 (0.50–1.91) | 0.94 |
Marital status | ||||||
Married/Partnered | 2362 | 5336 | 1772 | 33.2 | 1 | (ref) |
Widowed | 1908 | 4061 | 1409 | 34.7 | 1.22 (1.05–1.42) | 0.01 |
Divorced/Separated | 124 | 288 | 87 | 30.2 | 0.96 (0.74–1.24) | 0.76 |
Single | 240 | 477 | 188 | 39.4 | 1.34 (1.09–1.64) | < 0.01 |
Unknown | 67 | 146 | 50 | 34.2 | 1.2 (0.58–2.51) | 0.63 |
Cohabitation status | ||||||
Lives alone | 1144 | 2482 | 863 | 34.8 | 1 | (ref) |
Lives with spouse/partner | 2046 | 4596 | 1550 | 33.7 | 1.08 (0.92–1.28) | 0.33 |
Lives with someone other | 713 | 1519 | 512 | 33.7 | 1.1 (0.98–1.23) | 0.12 |
Domestic group | 497 | 1086 | 371 | 34.2 | 1.08 (0.94–1.24) | 0.27 |
Nursing home | 116 | 247 | 74 | 29.9 | 1.2 (0.74–1.95) | 0.46 |
Unknown | 185 | 379 | 136 | 35.9 | 1.07 (0.86–1.35) | 0.53 |
Caregiver | ||||||
None | 1842 | 4249 | 1404 | 33.1 | 1 | (ref) |
Spouse/Partner | 804 | 1733 | 628 | 36.2 | 1.43 (1.29–1.59) | < 0.01 |
Son/Daughter | 453 | 970 | 315 | 32.5 | 1.18 (1.03–1.35) | 0.02 |
Professional | 437 | 904 | 313 | 34.6 | 1.21 (1.06–1.38) | < 0.01 |
Residential Caregiver | 103 | 228 | 68 | 29.9 | 0.88 (0.53–1.45) | 0.6 |
Other | 1062 | 2225 | 778 | 35.0 | 1.24 (1.13–1.36) | < 0.01 |
Arthrosis | ||||||
no | 2032 | 4486 | 1551 | 34.6 | 1 | (ref) |
yes | 2536 | 5551 | 1866 | 33.6 | 0.95 (0.88–1.02) | 0.16 |
unknown | 133 | 272 | 89 | 32.7 | 0.89 (0.70–1.14) | 0.36 |
Depression | ||||||
no | 3108 | 6777 | 2319 | 34.2 | 1 | (ref) |
yes | 1319 | 2951 | 985 | 33.4 | 0.97 (0.90–1.05) | 0.41 |
unknown | 274 | 581 | 202 | 34.8 | 1.04 (0.88–1.23) | 0.63 |