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Table 1 Clinical diagnosis, sex, age, neuropathological assessment, cause of death and postmortem delay of cases included in the study

From: Neuronal CD59 isoforms IRIS-1 and IRIS-2 as regulators of neurotransmitter release with implications for Alzheimer’s disease

Groups

Clinical diagnosis

Sex

Age (years)

Neuropat. v (NFT/Aβ/LB)

Cause of death

PMD

Group 1 A

 

NC.1

M

72

2/O/0

Pneumonia

11:00

NC.2

F

55

1/O/0

Euthanasia (Chronic pain)

7:30

NC.3

F

75

1/A/0

Euthanasia (Heart failure)

6:57

Group1B

AD.1

M

94

5/C/0

End-stage dementia

6:20

AD.2

F

81

4/C/0

Pyelonephritis

6:30

AD.3

M

68

5/C/0

Euthanasia (AD)

6:32

 

AD.4

M

64

6/C/0

Euthanasia (AD)

6:65

AD.5

F

91

5/C/5

CVA

6:56

AD.6

M

72

6/C/0

Pneumonia

6:12

AD.7

M

82

5/C/0

AD

5:95

Group 2

NC.1

M

75

1/O/0

Cardiac arrest

7:10

NC.2

M

70

1/O/3

Pneumonia

6:59

NC.3

F

60

0/O/0

Mammary carcinoma

6:58

NC-T2D.1

F

60

0/O/0

Decreased intake

6:30

NC-T2D.2

F

68

1/O/0

Euthanasia (T2D)

4:30

NC-T2D.3

M

78

1/O/0

Euthanasia (T2D)

6:41

  1. NC = non-demented controls, AD = Alzheimer’s disease, NC-T2D = non-demented type 2 diabetes, NFT = Neurofibrillary tangles, LB = Lewy bodies, Aβ = amyloid beta. F = female, M = male. PMD = post mortem delay