Fig. 5

Correlations analysis among CEST/MRS measurements of Glu/GABA and cognition after 20-week treatment. (A) Correlation analysis between GluCEST and GABACEST signals and their concentrations by 1H-MRS in the hippocampus and cortex for four mouse groups. (B) Correlation analysis between MWM behavior metrics and GluCEST/GABACEST signals in the hippocampus and cortex. (C) Correlation analysis between MWM behavior metrics and Glu concentrations by 1H-MRS in the hippocampus and cortex