Fig. 1

Schematic diagram of retinal pathological changes in AD based on retinal OCT imaging features. A Retinal pathological changing patterns from normal to AD-derived dementia (ADD). B The correspondence between retinal pathological changes and OCT imaging features in AD, such as optical scattering property and structural morphology. C Retinal OCT imaging features quantization metrics, including OCT intensity spatial correlation features (OCT-ISCF) and thickness in different retinal sublayers. GCIPL, ganglion cells and inner plexiform layer, INL, inner nuclear layer; MEZ, myoid and ellipsoid zone; ONL, outer nuclear layer; OPL, outer plexiform layer; OS, outer segment of photoreceptor; RNFL, retinal nerve fiber layer; RPE, retinal pigment epithelium. This figure contains modified images from Servier Medical Art (https://smart.serviercom) licensed by a Creative Commons Attribution 3.0 Unported License