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Table 1 Clinical characteristics of subjects among CN, MCI, and ADD

From: Retinal optical coherence tomography intensity spatial correlation features as new biomarkers for confirmed Alzheimer’s disease

Characteristics

CN (n = 20)

MCI (n = 22)

ADD (n = 40)

P Value

Sex, No. (%)

 Male

6 (30)

11 (50)

15 (37)

0.40

 Female

14 (70)

11 (50)

25 (62)

Age, mean (SD), y

62.2 (6.2)

65.7 (8.3)

64.5 (7)

0.36

OCT image quality index

8.1 (0.8)

7.9 (0.8)

8.1 (0.9)

0.71

Hypertension, No. (%)

6 (30)

4 (18)

8 (20)

0.66

Diabetes, No. (%)

3 (15)

3 (13)

4 (10)

0.86

SE (D)

−0.8 (1.3)

−0.3 (2.0)

0.6 (1.1)

0.06

BCVA (logMAR)

0.04 (0.10)

0.05 (0.09)

0.05 (0.12)

0.88

IOP (mmHg)

15.7 (2.6)

15.1 (2.6)

15.2 (3.1)

0.77

MoCA

23.5 (2.9) b, c

17.0 (4.6) a, c

9.3 (4.7) a, b

 < 0.001*

CDR

0 b, c

0.5 a, c

1.3 (0.6) a, b

 < 0.001*

  1. Abbreviations: BCVA best corrected visual acuity, CDR Clinical Dementia Rating Scale, IOP Intraocular pressure, MoCA Montreal Cognitive Assessment, SD standard deviation, SE spherical equivalent refraction
  2. aStatistical difference with CN group
  3. bStatistical difference with MCI group
  4. cStatistical difference with ADD group;
  5. chi-square test
  6. *P < 0.05