Association of Alzheimer’s and Lewy body disease pathology with basal forebrain volume and cognitive impairment

Table 2 Group comparison of regional brain volumes

	Pure AD	Pure LBD	Mixed AD/ LBD	Overall group comparison	Pairwise comparisons
	Pure AD	Pure LBD	Mixed AD/ LBD	Overall group comparison	Pure AD vs. pure LBD	Pure AD vs. mixed	Pure LBD vs. mixed
Posterior BF volume	0.507 (0.059)	0.522 (0.064)	0.489 (0.057)	BF₁₀ = 32.8	BF₁₀ = 1.0	BF₁₀ = 16.2	BF₁₀ = 4.5
Anterior BF volume	0.777 (0.080)	0.799 (0.094)	0.774 (0.075)	BF₁₀ = 0.16	BF₁₀ = 0.9	BF₁₀ = 0.14	BF₁₀ = 0.58
Hippocampus volume	2.85 (0.46)	3.21 (0.49)	2.86 (0.38)	BF₁₀ = 41.5	BF₁₀ = 166.0	BF₁₀ = 0.11	BF₁₀ = 350

Mean (standard deviation) and group comparison by Bayesian ANCOVAs including covariates for age at MRI, sex, years of education, time between MRI and autopsy, and site. Volumes are presented as the ratio between regional grey matter volume and total intracranial volume
AD, Alzheimer’s disease; BF, basal forebrain; BF₁₀, Bayes factor in favor of H1 over H0; LBD, Lewy body disease

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