Table 3 CDR-SB Results by Subject and Visit– ITT Population
Cohort | Subject | AD Severity Stage | Baseline | Week 11/ Visit 5 | Week 22/ EOS | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Score | Score | CFB | Score | CFB |
1 | 002 | moderate | 13 | 15 | 2 | 16 | 3 |
003 | moderate | 12 | 12 | 0 | 12 | 0 | |
004 | mild | 8 | 8 | 0 | 11 | 3 | |
005 | mild | 4.5 | 3.5 | -1 | 4 | -0.5 | |
2 | 006 | severe | 16 | 18 | 2 | np | Â |
007 | mild | 6.5 | 5 | -1.5 | 7.5 | 1 | |
009 | severe | 18 | np | Â | np | Â | |
011 | mild | 4 | 6 | 2 | 6.5 | 2.5 | |
3 | 012 | severe | 18 | 18 | 0 | 18 | 0 |
014 | moderate | 10 | 5.5 | -4.5 | 7 | -3 | |
015 | mild | 6 | 6.5 | 0.5 | 7 | 1 | |
Medians (IQR) | 10 (6.0,16.0) | 7.25 (5.4,15.8) | 0.0 (-1.1, 2.0) | 7.5 (6.8,14.0) | 1.0 (-0.3, 2.8) | ||