From: Prediction of cognitive conversion within the Alzheimer’s disease continuum using deep learning
Actual reassignment status | Predicted reassignment status | |||
---|---|---|---|---|
Full model | Parsimonious model | |||
12-month | Overall, n (%) | 459/538 (85.32) | 485/538 (90.15) | 485/538 (90.15) |
Observation | 312/380 (82.11) | 334/380 (87.89) | 334/380 (87.89) | |
Monotherapy-ChEI | 93/101 (92.08) | 97/101 (96.04) | 95/101 (94.06) | |
Monotherapy-Memantine | 49/50 (98.00) | 48/50 (96.00) | 49/50 (98.00) | |
Combined therapy | 5/7 (71.43) | 6/7 (85.71) | 7/7 (100.00) | |
24-month | Overall, n (%) | 384/482 (79.67) | 435/482 (90.25) | 430/482 (89.21) |
Observation | 304/386 (78.76) | 341/386 (88.34) | 339/386 (87.82) | |
Monotherapy-ChEI | 54/62 (87.10) | 61/62 (98.39) | 59/62 (95.16) | |
Monotherapy-Memantine | 25/31 (80.65) | 31/31 (100.00) | 31/31 (100.00) | |
Combined therapy | 1/3 (33.33) | 2/3 (66.67) | 1/3 (33.33) | |
36-month | Overall, n (%) | 202/268 (75.37) | 219/268 (81.72) | 221/268 (82.46) |
Observation | 157/198 (79.29) | 170/198 (85.86) | 169/198 (85.35) | |
Monotherapy-ChEI | 36/50 (72.00) | 39/50 (78.00) | 38/50 (76.00) | |
Monotherapy-Memantine | 7/17 (41.18) | 10/17 (58.82) | 12/17 (70.59) | |
Combined therapy | 2/3 (66.67) | 0/3 (0.00) | 2/3 (66.67) | |
48-month | Overall, n (%) | 214/280 (76.43) | 232/280 (82.86) | 222/280 (79.29) |
Observation | 183/233 (78.54) | 199/233 (85.41) | 187/233 (80.26) | |
Monotherapy-ChEI | 26/35 (74.29) | 26/35 (74.29) | 27/35 (77.14) | |
Monotherapy-Memantine | 5/10 (50.00) | 7/10 (70.00) | 7/10 (70.00) | |
Combined therapy | 0/2 (0.00) | 0/2 (0.00) | 1/2 (50.00) |