Fig. 1

CSF β-syn levels in the cohorts of various diseases. A Comparison between the groups of total PrDs and non-PrDs. B Comparison among the groups of different PrDs (sCJD, T188K-gCJD, E200K-gCJD, P102L-GSS, D178N-FFI) and non-PrDs (AD, PD, VE, AE). β-syn values are presented as log (pg/ml); median, and interquartile range are shown for the biomarker levels. The p-values for the Mann–Whitney test are indicated above. The statistical outcomes of the corresponding PrDs, as compared to AD, PD, VE, AE, are represented by dark blue, sky blue, green, and cyan colors, respectively