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Table 3 Overview of determinants of global adherence to multimodal interventions identified in previous studies

From: Adherence and intensity in multimodal lifestyle-based interventions for cognitive decline prevention: state-of-the-art and future directions

Factors associated with poor adherence

Factors associated with good adherence

Lifestyle factors

- Current smoking status (9,14)

Psychosocial factors

- Depressive symptoms (9–11)

- Lower health-related quality of life (9,11)

- Higher Impact of memory problems on everyday life (12)

- Higher perceived risk of Alzheimer’s disease (12)

- Lower emotional stability (more anxious) (12)

- ≥ 1 Fried frailty criteria (12)

- Hopelessness (11)

- Nonpositive perception of the study (11)

Cardiovascular health

- Diabetes (9,10,12)

- Vascular risk (10)

- Obesity, higher body mass index (9,12,14)

- History of high blood pressure (9,14)

Sociodemographic factors

- Younger age (9,10,12)

- Married (10)

- Perceived social support (12)

- Smaller town (< 200,000) (12)

- Education (9)

Cognition

- Verbal memory (13)

- Processing speed (10)

- Global cognition (9,12)

- Attention and working memory (9)

Lifestyle factors

- Healthier lifestyle behaviors (multi-lifestyle score) (10)

- Physical activity (12)

- Diet score (10)

Psychosocial factors

- Functionality (14)