Fig. 1
The effect of cornuside on the learning and memory of Aβ1−42 intracerebroventricular injected mice in the behavioral tests. Data were expressed as the mean ± SEM (n = 13–15). A. Exploring routes during the navigation trial. B, C. Escape latency and average speed in the navigation trial. D. Exploring routes in the spatial probe trial. E, F. Latency to the platform and crossing times in the spatial probe trial. G, H. Representative nests built by mice, scored at 2 and 12 h in the nest building test. I. Discrimination index in the novel object recognition test. J. Spontaneous alternation rate in the Y-maze. K. Ratio of interaction with a novel mouse in the novel object recognition test. #p < 0.05 and ###p < 0.001 vs. control group; &p < 0.05 and &&p < 0.01 vs. sham group; *p < 0.05, **p < 0.01 and ***p < 0.001 vs. model group