Fig. 3
The effect of cornuside on neuron in the hippocampus and cortex of Aβ1−42 intracerebroventricular injected mice. Data were expressed as the mean ± SEM (n = 3–6). A, C. Representative images of TUNEL staining for the hippocampus and cortex, with a scale bar of 100 μm. B, D. The percentage of apoptotic cells in these regions. E, F. Representative images of IHC staining (scale bar: 100 μm) in CA3 and cortex. G Protein levels of NeuN in the hippocampus and cortex. H. TEM photomicrographs showing neuronal structures from different treatment groups (scale bar: 2 μm). The orange arrow indicates the nucleolus; the yellow arrow indicates the nuclear membrane; the blue arrow indicates mitochondrial ultrastructure; and the green arrow indicates the endoplasmic reticulum. #p < 0.05, ###p < 0.001 vs. control group; *p < 0.05, **p < 0.01 and ***p < 0.001 vs. model group