Fig. 3
From: TREM2 risk variants and associated endophenotypes in alzheimer’s disease
Main findings in this study. * CSF-NfL total n=165, TREM2 mutation carriers=10: R62H=4, R47H=3, T96K=2, other variants=1. Other TREM2 variants include: D87N, G58A, Q33X, C51Y, R47G, S31F, and A105V. Abbreviations: Aβ42 = Beta-Amyloid 42; CSF = Cerebrospinal fluid; HC = Hippocampus; MMSE = Mini-Mental State Examination; MRI = Magnetic Resonance Imaging; NA = Not Available; pTau-181: Phosphorylated Tau-181; TREM2 = Triggering Receptor Expressed on Myeloid Cells 2; = increased; ¯ = decreased