Table 1 Demographic data of early-onset AD patients and elderly healthy controls in our cohort
Total AD | Sporadic AD | Familial AD | Control | |
|---|---|---|---|---|
Cases, n | 304 | 244 | 60 | 292 |
Female, n (%) | 170 (55.9%) | 140 (57.4%) | 30 (50.0%) | 155 (53.1%) |
Age (years) | 57.5 ± 8.1 | 56.9 ± 7.7 | 62.5 ± 8.3 | 55.2 ± 15.4 |
AAO (years) | 55.5 ± 7.7 | 54.9 ± 7.1 | 58.9 ± 7.2 | - |
Disease duration (years) | 2.4 ± 2.7 | 2.2 ± 2.6 | 3.3 ± 3.0 | - |
MMSE score | 17.0 ± 8.7 | 16.9 ± 8.5 | 17.5 ± 9.7 | 27.4 ± 2.6 |
MoCA score | 12.4 ± 8.4 | 12.0 ± 8.3 | 13.7 ± 8.9 | 26.0 ± 3.1 |
Genetically diagnosed | 26 (8.6%) | 16 (6.6%) | 10 (16.7%) | - |