Fig. 4
From: Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer's disease
Glial cells moderate APP and MAPT interactions. a Workflow for network reconstruction from BIONIC analysis results, subnetwork construction using proteins highly associated with intermediary factors, APP and MAPT, and community detection within the network, followed by cell type identification and enrichment analyses for each community. b GO enrichment analysis of the subnetwork, categorized by parent terms using the rrvgo [45] software. c Representative GO terms enriched in each community. d Dotplot displaying expression levels of proteins within each community