Fig. 7
From: Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer's disease
GPNMB + microglia as a possible moderator of the Aβ-tau interaction. a, b Heatmaps displaying the correlations between CERAD and Braak scores in samples categorized by the top (a) and bottom (b) 35% of GPNMB expression. c Significant results of linear regression analyses for each of the four distinct brain regions, with subjects categorized into no-dementia and dementia groups. d Schematic representation summarizing the findings supporting the roles of both astrocytes and GPNMB+ microglia in the Aβ-tau interaction