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Table 1 Correlation between ALPS indices and amyloid beta42/40 ratio

From: Perivascular space and white matter hyperintensities in Alzheimer’s disease: associations with disease progression and cognitive function

 

ActiGlia

ADNI

DELCODE

Aβ42/40

Aβ42/40

Aβ42/40

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

ALPS_comb

-0.14

0.34

0.31

0.675

-0.17

0.40

0.05

0.670

-0.65

0.24

0.15

0.009*

ALPS_R

-0.08

0.31

0.39

0.796

-0.06

0.35

0.25

0.877

-0.58

0.25

0.11

0.020*

ALPS_L

-0.18

0.35

0.23

0.621

-0.06

0.40

0.06

0.891

-0.56

0.24

0.13

0.022*

  1. Abbreviations: ALPS_R, ALPS_L: calculated ALPS index on right R and left L hemisphere of the brain. ALPS_comb: combined ALPS index, by calculating the mean of Index for right and left hemishphere; adj-R²: adjusted R²; SE: Standard error; * significant difference with P < 0.05. Calculated with multivariate linear regression analyses, using age, sex, years of education and diagnose (ADvsHC) as confounding variables
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Alzheimer's Research & Therapy

ISSN: 1758-9193