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Table 2 Correlation between ALPS indices and amyloid beta42/40 ratio in AD group

From: Perivascular space and white matter hyperintensities in Alzheimer’s disease: associations with disease progression and cognitive function

 

ActiGlia

ADNI

DELCODE

Aβ42/40

Aβ42/40

Aβ42/40

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

ALPS_comb

-0.33

0.03

0.48

0.138

-0.26

8.50

-0.08

0.255

-0.40

2.30

0.23

0.003*

ALPS_R

-0.18

0.04

0.57

0.345

-0.30

5.22

0.07

0.167

-0.45

2.50

0.32

0.000*

ALPS_L

-0.45

0.03

0.10

0.125

-0.13

5.43

-0.06

0.575

-0.26

2.60

0.08

0.062

  1. Abbreviations: ALPS_R, ALPS_L: calculated ALPS index on right R and left L hemisphere of the brain. ALPS_comb: combined ALPS index, by calculating the mean of Index for right and left hemishphere; adj-R²: adjusted R²; SE: Standard error; * significant difference with P < 0.05. Calculated with multivariate linear regression analyses, using age, sex, and years of education as confounding variables
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Alzheimer's Research & Therapy

ISSN: 1758-9193