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Table 4 Correlation between ALPS indices and Amyloid-beta 42

From: Perivascular space and white matter hyperintensities in Alzheimer’s disease: associations with disease progression and cognitive function

 

ActiGlia

ADNI

DELCODE

Aβ42

Aβ42

Aβ42

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

β

SE

Adj-R²

p-value

ALPS_comb

0.47

0.19

0.43

0.019*

0.25

0.19

0.04

0.206

0.25

0.16

0.11

0.124

ALPS_R

0.31

0.18

0.45

0.104

0.27

0.17

0.24

0.133

0.30

0.16

0.09

0.071

ALPS_L

0.53

0.19

0.39

0.010*

0.35

0.19

0.10

0.072

0.13

0.16

0.10

0.416

  1. Abbreviations: ALPS_R, ALPS_L: calculated ALPS index on right R and left L hemisphere of the brain. ALPS_comb: combined ALPS index, by calculating the mean of Index for right and left hemishphere; adj-R2: adjusted R2; SE: Standard error; * significant difference with P < 0.05. Calculated with multivariate linear regression analyses, using age, sex years of education and diagnose (ADvsHC) as confounding variables
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Alzheimer's Research & Therapy

ISSN: 1758-9193