From: Diabetes status, duration, and risk of dementia among ischemic stroke patients
Subgroup | Glycemic Status | N | All-cause Dementia | IR, per 1000 PY | HR (95% CI) | |||
---|---|---|---|---|---|---|---|---|
Model1 | Model2 | Model3 | ||||||
Age | 40–64 | Normal | 30,592 | 1,365 | 5.51 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
IFG | 14,434 | 624 | 5.36 | 0.974 (0.886,1.071) | 0.962 (0.875,1.058) | 0.960 (0.873,1.056) | ||
NODM | 633 | 31 | 6.23 | 1.135 (0.795,1.621) | 1.172 (0.821,1.673) | 1.148 (0.804,1.639) | ||
< 5 years | 5,826 | 366 | 7.96 | 1.452 (1.294,1.630) | 1.375 (1.225,1.544) | 1.345 (1.197,1.511) | ||
≥ 5 years | 5,595 | 523 | 12.21 | 2.238 (2.024,2.476) | 1.893 (1.710,2.095) | 1.836 (1.658,2.033) | ||
≥ 65 | Normal | 29,773 | 7,885 | 39.25 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) | |
IFG | 15,439 | 3,992 | 38.34 | 0.977 (0.940,1.015) | 0.988 (0.951,1.026) | 0.983 (0.946,1.021) | ||
NODM | 870 | 235 | 45.58 | 1.182 (1.038,1.346) | 1.006 (0.884,1.146) | 0.992 (0.871,1.130) | ||
< 5 years | 6,797 | 2,021 | 45.92 | 1.178 (1.122,1.237) | 1.267 (1.206,1.332) | 1.248 (1.188,1.312) | ||
≥ 5 years | 8,831 | 2,802 | 51.23 | 1.326 (1.270,1.385) | 1.430 (1.369,1.494) | 1.399 (1.338,1.462) | ||
p for interaction | < 0.0001 | < 0.0001 | < 0.0001 | |||||
Sex | Male | Normal | 26,680 | 3,588 | 18.43 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
IFG | 15,239 | 1,927 | 17.23 | 0.934 (0.884,0.988) | 0.968 (0.915,1.023) | 0.973 (0.921,1.029) | ||
NODM | 865 | 112 | 19.02 | 1.039 (0.861,1.254) | 0.980 (0.812,1.183) | 0.967 (0.801,1.168) | ||
< 5 years | 6,793 | 1,029 | 21.34 | 1.162 (1.084,1.245) | 1.295 (1.207,1.388) | 1.276 (1.190,1.369) | ||
≥ 5 years | 7,441 | 1,363 | 27.16 | 1.490 (1.400,1.586) | 1.438 (1.351,1.532) | 1.410 (1.323,1.502) | ||
Female | Normal | 33,685 | 5,662 | 22.29 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) | |
IFG | 14,634 | 2,689 | 24.74 | 1.112 (1.062,1.164) | 0.994 (0.949,1.041) | 0.982 (0.938,1.029) | ||
NODM | 638 | 154 | 36.26 | 1.648 (1.404,1.934) | 1.026 (0.874,1.204) | 1.011 (0.861,1.187) | ||
< 5 years | 5,830 | 1,358 | 32.52 | 1.468 (1.384,1.558) | 1.281 (1.207,1.360) | 1.260 (1.186,1.338) | ||
≥ 5 years | 6,985 | 1,962 | 41.45 | 1.887 (1.793,1.987) | 1.547 (1.469,1.630) | 1.507 (1.430,1.588) | ||
p for interaction | < 0.0001 | 0.4422 | 0.5317 |