Fig. 3

Effects of PBM on the phenotype of microglia in mice with AD. A Representative images of anti-CD86 and anti-Arg-1 immunolabelled microglia in the mouse cortex. Scale bar: 20 μm. A magnified images show typical microglia expressing CD86/Arg-1. Scale bar: 5 μm. B Quantitative analysis of the fluorescence intensity and relative ratio of CD86 and Arg-1 in mouse microglia. C Exemplary protein immunoblotting and quantification of CD86 and Arg-1 in mouse brain tissue. Experimental data are presented as the mean ± standard deviation. Compared with the CON group, *p < 0.05, **p < 0.01, ***p < 0.001; Compared with the AD group, #p < 0.05, ##p < 0.01, ###p < 0.001