Fig. 6

PBM inhibits neuronal apoptosis in mice with AD. A-B Analysis of JC-1 flow cytometry results in the mouse brain tissue. C Immunohistochemical staining of mouse brains using an anti-Cytc antibody (scale bars 100 μm and 20 μm, respectively) with arrows indicating Cytc. D ELISA was used to detect Cytc in mouse brain tissue. E WB was used to detect Caspase3, Caspase9, and Cytc in the mouse brain tissue. F RT-PCR was used to detect Bcl-2, Bax, Caspase3, Caspase9, and Cytc in mouse brains. Experimental data are presented as the mean ± standard deviation. Compared with the CON group, *p < 0.05, **p < 0.01, ***p < 0.001; Compared with the AD group, #p < 0.05, ##p < 0.01, ###p < 0.001