Fig. 5
From: Novel CSF β-synuclein-specific assays signal early synaptic degeneration in Alzheimer’s disease
ROC curves for β-syn (N-terminus, mid-region, and C-terminus) and Aβ42 levels, and β-syn/Aβ42 ratios. The figure depicts their diagnostic performance in distinguishing between SCD controls and SCD-AD (A), MCI-AD (B) and AD-dem (C). SCD-AD: subjective cognitive decline due to AD, MCI-AD: mild cognitive impairment due to AD, AD-dem: dementia due to AD, β-syn: beta-synuclein, Aβ42: amyloid beta (1-42), ROC: receiver operating characteristic, AUC: area under the curve