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Table 1 Clinical characteristics and neuropsychological test results

From: Impact of effective connectivity within the Papez circuit on episodic memory: moderation by perivascular space function

Characteristics

HCs

aMCI

T/χ2

P

N

32

28

-

-

Age (y), mean (SD)

64.63 (6.56)

67.14 (7.24)

-1.413

0.163

Education (y), mean (SD)

11.78 (3.05)

11.61 (3.10)

0.219

0.827

Female, N (%)

25 (78.13)

16 (57.14)

3.038

0.081

Smoke, N (%)

4 (12.50)

6 (21.43)

0.857

0.355

Drink, N (%)

5 (15.63)

4 (14.29)

0.021

0.885

Height (cm), mean (SD)

163.77 (6.06)

160.92 (12.64)

1.031

0.310

Weight (kg), mean (SD)

62.04 (9.92)

62.68 (12.48)

-0.211

0.833

FDJenkinson

0.067 (0.026)

0.081 (0.033)

-0.013

0.093

FDPower

0.118 (0.036)

0.132 (0.034)

-0.014

0.141

MMSE, mean (SD)

28.47 (1.50)

27.25 (1.58)

3.062

0.003

MoCA-B, mean (SD)

26.44 (1.90)

22.46 (3.00)

6.208

< 0.001

AVLT, mean (SD)

60.53 (8.70)

35.61 (4.91)

13.882

< 0.001

AVLT-N1, mean (SD)

4.09 (1.30)

2.96 (0.92)

3.821

< 0.001

AVLT-N2, mean (SD)

6.84 (1.61)

4.46 (0.96)

7.051

< 0.001

AVLT-N3, mean (SD)

8.28 (1.46)

5.25 (1.27)

8.517

< 0.001

AVLT-N4, mean (SD)

6.69 (1.62)

2.36 (1.31)

11.295

< 0.001

AVLT-N5, mean (SD)

6.28 (1.75)

1.54 (1.29)

11.828

< 0.001

AVLT-N6, mean (SD)

6.09 (2.36)

1.89 (1.34)

8.602

< 0.001

AVLT-N7, mean (SD)

22.25 (1.44)

17.14 (1.78)

12.296

< 0.001

FAQ, mean (SD)

0.22 (0.91)

0.96 (1.71)

-2.067

0.045

TIV (cm3), mean (SD)

1388.66 (117.86)

1434.02 (124.18)

-1.451

0.152

LACC (cm3), mean (SD)

0.36 ± 0.04

0.35 ± 0.04

0.693

0.491

LATN (cm3), mean (SD)

0.26 ± 0.03

0.25 ± 0.03

0.452

0.653

LERC (cm3), mean (SD)

0.47 ± 0.06

0.47 ± 0.08

0.357

0.722

LHPC (cm3), mean (SD)

0.41 ± 0.04

0.39 ± 0.06

1.463

0.150

LMB (cm3), mean (SD)

0.14 ± 0.02

0.14 ± 0.01

0.216

0.830

LPCC (cm3), mean (SD)

0.36 ± 0.06

0.35 ± 0.05

0.523

0.603

LPHG (cm3), mean (SD)

0.39 ± 0.03

0.39 ± 0.04

0.745

0.459

LSub (cm3), mean (SD)

0.47 ± 0.05

0.45 ± 0.07

1.706

0.093

RACC (cm3), mean (SD)

0.28 ± 0.03

0.27 ± 0.03

1.543

0.128

RATN (cm3), mean (SD)

0.25 ± 0.02

0.25 ± 0.03

0.519

0.606

RERC (cm3), mean (SD)

0.42 ± 0.06

0.42 ± 0.07

-0.027

0.979

RHPC (cm3), mean (SD)

0.39 ± 0.04

0.37 ± 0.05

1.377

0.174

RMB (cm3), mean (SD)

0.14 ± 0.02

0.14 ± 0.01

0.355

0.724

RPCC (cm3), mean (SD)

0.27 ± 0.04

0.26 ± 0.04

0.491

0.625

RPHG (cm3), mean (SD)

0.44 ± 0.04

0.44 ± 0.05

0.659

0.512

RSub (cm3), mean (SD)

0.49 ± 0.06

0.47 ± 0.06

1.445

0.154

Left hippocampal volume supplied by the choroidal artery

0.60 ± 0.07

0.56 ± 0.10

1.606

0.114

Left hippocampal volume supplied by the hippocampal artery

2.82 ± 0.32

2.69 ± 0.41

1.324

0.191

Right hippocampal volume supplied by the choroidal artery

0.62 ± 0.07

0.60 ± 0.07

1.045

0.301

Right hippocampal volume supplied by the hippocampal artery

9.82 ± 1.09

9.44 ± 1.28

1.243

0.219

  1. aMCI, amnestic mild cognitive impairment; HCs, healthy controls; BMI, body mass index; MMSE, Mini-Mental State Examination; MoCA-B, Montreal Cognitive Assessment-Basic; AVLT, Auditory Verbal Learning Test; AVLT-N1, Auditory Verbal Learning Test, First Immediate Recall; AVLT-N2, Auditory Verbal Learning Test, Second Immediate Recall; AVLT-N3, Auditory Verbal Learning Test, the Third Immediate Recall; AVLT-N4, Auditory Verbal Learning Test, Short-Term Delay Recall; AVLT-N5, Auditory Verbal Learning Test, Long-Term Delay Recall; AVLT-N6, Auditory Verbal Learning Test, Long Delay Cued Recall; AVLT-N7, Auditory Verbal Learning Test, Recognition; FAQ, Functional Activities Questionnaire; TIV, total intracranial volume; FD, framewise displacement