Table 1 Demographic, clinical, magnetic resonance imaging and self-reported and objective sleep characteristics
Variables | n (%) or median (Q1-Q3) |
|---|---|
Demographic and clinical characteristics (n = 678) | |
Sex | |
Men | 323 (47.64) |
Women | 355 (52.36) |
Age (years) | 70.7 (67.8–74.0) |
Educational level | |
≥ Primary | 501 (73.89) |
< Primary | 177 (26.11) |
APOE ε4 carrier | |
< 1 allele | 539 (79.50) |
≥ 1 allele | 139 (20.50) |
Alcohol (g/day) | |
< 12 | 395 (59.58) |
[12;36[ | 189 (28.51) |
≥ 36 | 79 (11.92) |
History of cardiovascular diseases | |
No | 558 (82.42) |
Yes | 119 (17.58) |
Cardiovascular health score | 8.0 (7.0–10.0) |
Depressive status a | |
No | 484 (71.81) |
Yes | 190 (28.19) |
Sleeping pills b | |
No | 571 (84.22) |
Yes | 107 (15.78) |
MRI characteristics (n = 678) | |
Intracranial volume (cm3) | 1190.2 (1115.9-1273.6) |
Hippocampus volume (cm3) | 5.8 (5.2–6.2) |
Hippocampus volume (cm3) | |
≥ 5.4 (2nd and 3rd tertiles) | 435 (68.2) |
< 5.4 (1st tertile) | 203 (31.8) |
White matter hyperintensities volume (cm3) | 0.70 (0.30–2.70) |
White matter hyperintensities volume (cm3) | |
≤ 1.6 (1st and 2nd tertiles) | 455 (67.51) |
> 1.6 (3rd tertile) | 219 (32.49) |
Self-reported sleep characteristics (n = 678) | |
Nighttime sleep duration (h) | |
≤ 6 | 201 (31.41) |
]6;9[ | 370 (57.81) |
≥ 9 | 69 (10.78) |
Napping | |
No | 355 (53.79) |
Infrequent/short | 108 (16.36) |
Regular long | 197 (29.85) |
Sleep efficiency | |
Good (≥ 85%) | 315 (49.45) |
Poor (< 85%) | 322 (50.55) |
Bedtime | |
≤ 9 pm | 37 (5.48) |
]9–11[ pm | 255 (37.78) |
≥ 11 pm | 383 (56.74) |
Rising time | |
≤ 6 am | 78 (11.56) |
]6–8] am | 492 (72.89) |
> 8 am | 105 (15.56) |
Excessive daytime sleepiness | |
No | 600 (90.91) |
Yes | 60 (9.09) |
Satisfaction in sleep quality | |
Yes | 500 (75.41) |
No | 163 (24.59) |
Number of insomnia symptoms | |
0 | 196 (29.97) |
1 | 254 (38.84) |
2–3 | 204 (31.19) |
Objective (via polysomnography) characteristics (n = 176) | |
Nighttime sleep duration (h) | 6.1 (5.4–6.9) |
N1 sleep duration (min) | 22.5 (14.8–30.0) |
% N1 sleep duration | 6.0 (4.1–8.4) |
N2 sleep duration (min) | 227.8 (194.3-260.3) |
% N2 sleep duration | 61.9 (57.9–68.1) |
N3 sleep duration (min) | 39.8 (25.3–58.0) |
% N3 sleep duration | 11.4 (7.3–15.9) |
REM sleep duration (min) | 71.0 (54.8–85.0) |
% REM sleep duration | 19.3 (15.6–22.8) |
SB duration (min) | 27.3 (17.8–40.8) |
SB NREM duration (min) | 4.0 (2.5–7.3) |
SB REM duration (min) | 0.0 (0.0–4.0) |
Sleep efficiency (%) | 67.9 (60.6–75.6) |
Sleep latency (min) | 86.5 (64.5-134.8) |
WASO (min) | 173.8 (130.5-218.8) |
AHI (/h) | 4.0 (1.3–11.8) |
iPLMS | 23.3 (9.8–43.1) |
O2 desaturation index > 3% | 7.0 (3.0–15.0) |