Fig. 2

Group Comparisons of regional volume between controls and clinical AD phenotype groups. AAL3 atlas regions are grouped by lobes and brain structures and sorted in alphabetical order. Comparisons in order from outer ring to inner ring: control vs typical AD, control vs atypical AD, typical AD vs atypical AD. Volume differences are displayed as Cohen's D effect sizes, with negative effect size (blue) denoting a lower volume in the second group of each paired comparison. Significant group differences are annotated with * = p ≤ 0.05, corrected for multiple comparisons. Highlighted in red boxes are regions selected for association with pathological quantification