Table 3 Subgroup analysis of the hazard ratio of Alzheimer’s disease between treated- and untreated-group

sex

Male

0.50

0.19

1.33

0.1656

ref.

Female

0.45

0.21

0.99

0.0463

0.8679

Age

< 65 years

0.22

0.08

0.57

0.0019

ref.

≥ 65 years

1.23

0.50

3.02

0.6561

0.010

Socioeconomic status

Income > 75%

0.62

0.20

1.91

0.4082

ref.

Income 25–75%

0.40

0.16

1.03

0.0577

0.5514

Income < 25%

0.45

0.14

1.45

0.1785

0.6842

Level of health care

Tertiary hospital

0.57

0.24

1.36

0.2039

ref.

Secondary hospital

0.40

0.16

1.03

0.0576

0.5890

Primary hospital

0.34

0.04

3.23

0.3443

0.6689

Cirrhosis

No

0.31

0.12

0.85

0.0232

ref.

Yes

0.62

0.28

1.37

0.2410

0.2896

Diabetes mellitus

No

0.50

0.24

1.03

0.0607

ref.

Yes

0.40

0.13

1.27

0.1193

0.7426

Hypertension

No

0.28

0.10

0.75

0.0113

ref.

Yes

0.71

0.32

1.60

0.4073

0.1516

Dyslipidemia

No

0.14

0.04

0.48

0.0016

ref.

Yes

1.09

0.48

2.47

0.8350

0.0063

Chronic kidney disease

No

0.47

0.25

0.87

0.0155

ref.

Yes

Inf.

Inf.

Inf.

Inf.

Inf.

Congestive heart failure

No

0.44

0.23

0.82

0.0099

ref.

Yes

Inf.

Inf.

Inf.

Inf.

Inf.

Ischemic heart disease

No

0.41

0.21

0.81

0.0103

ref.

Yes

0.97

0.20

4.78

0.9654

0.3388

Traumatic brain injury

No

0.47

0.25

0.87

0.0155

ref.

Yes

Inf.

Inf.

Inf.

Inf.

Inf.