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Table 5 Results from Cox regression model evaluating the association between Methylation-based Resilience Score (MRS) and disease progression (CN to MCI/AD, MCI to AD) in 538 subjects, adjusted for age, sex, APOE ε4 status, baseline diagnosis, MMSE, and education. Significant association was observed for MRS (estimate = − 0.035, P-value = 0.00406), indicating higher MRS reduces risk of progression in AD

From: DNA methylation signature of a lifestyle-based resilience index for cognitive health

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Alzheimer's Research & Therapy

ISSN: 1758-9193